健康体检人群身体测量指标与2型糖尿病的关系

Relationship between anthropometric measures and type 2 diabetes in health check-up crowd

摘要:

目的  探讨健康体检人群身体测量指标与2型糖尿病（T2DM）的关系。方法  选取2011年1月-2015年4月在宁夏医科大学总医院进行体检的4 186例成人作为研究对象，根据其血糖情况分为T2DM组和非T2DM组。通过单因素分析和多非条件Logistic多元回归探讨各身体测量指标与T2DM发病的关系。结果  4 186例受试者中220例发现T2DM，占5.3%。T2DM组的体重指数（BMI）、体脂比、腰围（WC）、臀围、腰臀比（WHR）及腰身比（WHtR）均显著高于非T2DM组（P <0.05）。非条件Logistic多元回归分析结果表明调整年龄、文化程度、饮酒、吸烟和糖尿病（DM）家族史等混杂因素影响后，BMI、体脂比、WC、臀围、WHR及WHtR等各身体测量指标均与T2DM患病呈显著正相关（P <0.05），且以WHR为主的腹型肥胖指标与其关系更密切。结论  对于健康体检人群而言，身体测量指标与T2DM的发病密切相关，其中以WHR为主的腹型肥胖指标的影响更大，故建议通过调整饮食和运动来控制WHR，尽可能预防T2DM的发生。

Abstract:

Objective To study the relationship between anthropometric measures and type 2 diabetes (T2DM) in health check-up crowd. Methods From January 2011 to April 2015, 4,186 residents who received health examination in our hospital were selected and divided into T2DM group and non-T2DM group. The single factor analysis and unconditioned multivariate logistic regression analysis were performed to investigate the relationship between anthropometric measures and prevalence of T2DM. Results 220 cases (5.3%) of T2DM were found in 4186 subjects. BMI, body fat ratio, waist circumference (WC), hip circumference, waist-to-hip ratio (WHR), waist-to-height ratio (WHtR) in T2DM group were significantly higher than in non-T2DM group (P < 0.05). Results of unconditioned multivariate logistic regression analysis showed that all anthropometric measures were significantly positively related with T2DM after adjustment for age, cultural degree, drinking, smoking, family history of DM and other confounding factors (P < 0.05), and the relationship between abdominal obesity indexes like WHR and T2DM was closer. Conclusions For health check-up crowd, anthropometric measures are closely related to prevalence of T2DM, and the impact of abdominal obesity indexes like WHR is bigger, which suggests diet adjustment and exercise to control WHR can prevent T2DM.