Abstract:Objective To investigate hand hygiene compliance of healthcare workers in the Department of Dermatology and Venereology. Methods Sixty-five healthcare workers were surveyed on site regarding hand hygiene compliance through a self-designed questionnaire. Results The vast majority of healthcare workers understood the importance of hand hygiene in controlling hospital-acquired infections. However, the overall hygiene compliance rate was only 54.06% on average, while the hygiene compliance rates of medical staff from different positions were different (χ2 = 8.429, P = 0.015), with medical technicians having a significantly lower rate (47.74%) than doctors (55.13%) and nursers (56.35%). The hand hygiene compliance rates before patient-contact (29.75%), before aseptic-tasks (71.59%), after body fluid-exposure (83.78%), after patient-contact (51.47%) and after contact with patient surroundings (42.86%) were not all identical (χ2 = 262.956, P = 0.000); there were also differences in compliance rates between different professions at different time. In addition, heavy workloads were the main factor influencing hand hygiene performance, while the insufficient facilities had the least impact. Conclusions Hand hygiene compliance of healthcare workers in the Department of Dermatology and Venereology is low. Therefore, education, training, monitoring and other interventions are required to improve hand hygiene awareness and compliance.