麒麟丸联合人绝经期促性腺激素治疗未破裂卵泡黄素化综合征的疗效研究

Clinical effects of Qilin pills combined with HMG on patients with luteinized unruptured follicle synodrome

摘要:

目的  观察麒麟丸联合人绝经期促性腺激素（HMG）治疗未破裂卵泡黄素化综合征（LUFS）的临床疗效。方法  将门诊69例未破裂卵泡黄素化综合征患者，随机分为治疗组（A组35例）和对照组（B组34例），两组用HMG注射治疗，A组加以口服麒麟丸联合治疗。观察比较两组治疗后排卵率、妊娠率和不同时间血清黄体生成素（LH）、卵泡刺激素（FSH）、雌二醇（E2）、孕酮（P）的差异。结果  两组排卵率（76.1% vs 59.8%）、妊娠率（40.0% vs 17.6%）比较，差异有统计学意义（P <0.05）。A组卵泡成熟日血LH和E2值、排卵后1周血P值均显著高于B组（P <0.05）。结论  麒麟丸联合HMG治疗LUFS可明显提高排卵率和妊娠率。

Abstract:

Objective To study the clinical effects of Qilin pills combined with HMG on patients with luteinized unruptured follicle synodrome (LUFS). Methods Sixty-nine patients with LUFS were assigned into a trial group (group A, 35 cases) and a control group (group B, 34 cases) who were treated with Qilin pills combined with HMG and HMG alone, respectively. The ovulation rate, natural pregnancy rate and the levels of serum sex hormones (LH, FSH, E2 and P) of the two groups were compared after treatment. Results The ovulation rates (76.1% vs 59.8%) and natural pregnancy rates (40.0% vs 17.6%) were significant different between the groups A and B after treatment (P < 0.05).  In additional, the levels of LH and E2 on the follicle maturity day, and the level of P in one week after induced ovulation in the group A were obviously higher than those in the group B (P < 0.05). Conclusions Qilin pills combined with HMG can significantly enhance the ovulation and natural pregnancy rate in patients with LUFS.