Abstract:Objective To explore the role of 3D printing technology in improving accuracy of the reconstruction of mandibular defect with vascularized fibula graft in 80 cases. Methods For 80 cases of mandibular disease patients simulation of lesion resection and repair and reconstruction with fibular graft were completed using computer-aided design software. The entity model after reconstruction and digital guide for guidance of bone section and bone remodeling were printed out, and then reconstruction plates were made according to pre-bending of the model. The patients had CT scan again one week after operation. The patients' CT data were input to the computer-aided design software, then the lateral length errors of mandible buccal lingual side and medial and lateral fibula sides were compared between the actual operation and simulated osteotomy. Results The mandible buccal side error between actual surgical resection of the mandible and simulated surgery resection was(0.99 ± 1.06) mm, while the mandibular lingual side error was (1.47 ± 1.30) mm between actual and simulated surgical osteotomy of mandibula. The fibula medial side error between the actual operation excision and simulated surgical excision was (1.41 ± 0.97) mm, while the fibula lateral error between the actual operation excision and simulated surgical excision was (1.62±1.46) mm. Conclusions The use of 3D printing technology can obtain high accuracy in the reconstruction of mandibular defect with vascularized fibula graft.