Abstract:Objective To investigate the influence of using individual health education and WeChat on cognitive performance in patients with type 2 diabetes. Methods The demographic and clinical data of 53 type 2 diabetes (T2DM) (male : female = 30 : 23) patients were collected. The repeatable battery for the assessment of neuropsychological status (RBANS) was applied to assess their cognitive function. The patients received individual health education for six months. The fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c) and cognitive performance were measured and compared before and after education, the factors related to the increased value of cognitive performance in T2DM patients were investigated. Results In the T2DM patients, the FPG and HbA1c values after individual and WeChat health education were lower than those before education (P < 0.05), the delayed memory performance after individual and WeChat health education was higher than that before education [(86.9 ± 13.5) vs (80.4 ± 14.9), P < 0.05]. After individual and WeChat health education for 6 months, the decreased HbA1c value was positively correlated with the increased value of delayed memory (r = 0.353, P = 0.020) and RBANS total score (r = 0.327, P = 0.045). Furthermore, the decreased HbA1c value was also positively correlated with the increased value of delayed memory in linear regression analysis (P < 0.05). Conclusions Individual and WeChat health education can ameliorate cognitive impairment in patients with T2DM, especially in delayed memory.