颌骨囊肿术后骨缺损治疗中口腔胶原膜联合β-磷酸三钙治疗的价值分析
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浙江中医药大学口腔医学院

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Analysis of the Value of Oral Repair Membrane Combined with β-Tricalcium Phosphate in the Treatment of Bone Defects after Jaw Cyst
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    摘要:

    目的:探讨颌骨囊肿术后骨缺损治疗中口腔胶原膜联合β-磷酸三钙治疗的价值。方法:选取浙江中医药大学附属口腔医院2015年1月至2020年1月收治的牙源性颌骨囊肿并行手术治疗的162例患者为研究对象,根据随机数字表法分为3组,每组54例,A组(对照组):术后不放置任何材料;B组(胶原膜组):术后使用胶原膜覆盖骨缺损部位;C组(植骨胶原膜组):术后使用β-TCP进行填塞,且使用胶原膜覆盖。所有患者均在术前及术后3、6、12月进行锥形束CT(CBCT)检查,测定其骨缺损区域的骨密度。结果:所有患者均未发生复发情况。CBCT检查HUT值比较显示:术前三组比较差异无统计学意义(P>0.05);组内不同时间比较差异显著(P<0.05),且随着时间推移,HUT值逐渐增大;术后3、6、12个月三组间差异具有统计学意义(P<0.05),且C组显著大于A、B组(P<0.05),B组显著大于C组(P<0.05)。结论:颌骨囊肿术后骨缺损治疗采用胶原膜联合β-TCP具有较为理想的成骨效果,临床价值较高。

    Abstract:

    Objective: To explore the value of oral repair membrane combined with β-tricalcium phosphate in the treatment of bone defect after jaw cyst. Methods: 162 patients with odontogenic jaw cysts treated with surgical treatment from January 2015 to January 2020 in the Dental Hospital of Zhejiang Chinese Medical University were selected as the research objects, and they were divided into 3 groups according to the random number table method. There are 54 cases in each group, group A (control group): no materials are placed after surgery; group B (repair membrane group): repair membrane is used to cover the bone defect after surgery; group C (bone graft repair membrane group): use after surgery β-TCP is stuffed and covered with a repair film. All patients underwent cone-beam CT (CBCT) examinations before and 3, 6, and 12 months after the operation to determine the bone mineral density in the bone defect area. Results: No recurrence occurred in all patients. The comparison of HUT value in CBCT examination showed that the difference between the three groups before operation was not statistically significant (P>0.05); the difference was significant at different times within the group (P<0.05), and the HUT value gradually increased with the passage of time; The differences between the three groups at 3, 6, and 12 months were statistically significant (P<0.05), and the C group was significantly larger than the A and B groups (P<0.05), and the B group was significantly larger than the C group (P<0.05). Conclusion: The repairing membrane combined with β-TCP in the treatment of bone defects after jaw cyst has an ideal osteogenic effect and high clinical value.

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  • 收稿日期:2021-06-11
  • 最后修改日期:2021-09-10
  • 录用日期:2021-10-08
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