Abstract:Objective To explore the efficacy of collagen membrane combined with β-tricalcium phosphate (β-TCP) in the treatment of jaw defects after cyst enucleation.Methods A total of 162 patients with odontogenic jaw cysts undergoing surgical treatments in Stomatology Hospital Affiliated to Zhejiang Chinese Medical University from January 2015 to January 2020 were selected, and they were divided into 3 groups according to the random number table method, with 54 cases in each group. Group A did not receive any filling materials after surgery. The collagen membrane was applied to cover the jaw defects after surgery in group B. In contrast, the bone defects were filled with β-TCP and covered with collagen membrane after surgery in group C. All patients underwent cone-beam CT (CBCT) before the operation and 3, 6, and 12 months after the operation to determine the bone mineral density of the defect areas.Results None of the patients relapsed after the surgery. The repeated measurement of CT value via CBCT in the three groups before the operation and 3, 6, and 12 months after the operation demonstrated that there were differences in the CT value of the groups at distinct time points (F =34.335, P =0.000), and that the CT value increased over time (P < 0.05). The CT value was also different among the three groups (F =9.634, P =0.008), and was highest in the group C (P < 0.05) but lowest in the group A (P < 0.05). In addition, the change trend of CT value was different among the groups (F =165.591, P =0.000).Conclusions The collagen membrane combined with β-TCP is effective in promoting the bone formation for jaw defects after cyst enucleation, and is therefore of great value in clinical practice.