Objective: To explore the value of oral repair membrane combined with β-tricalcium phosphate in the treatment of bone defect after jaw cyst. Methods: 162 patients with odontogenic jaw cysts treated with surgical treatment from January 2015 to January 2020 in the Dental Hospital of Zhejiang Chinese Medical University were selected as the research objects, and they were divided into 3 groups according to the random number table method. There are 54 cases in each group, group A (control group): no materials are placed after surgery; group B (repair membrane group): repair membrane is used to cover the bone defect after surgery; group C (bone graft repair membrane group): use after surgery β-TCP is stuffed and covered with a repair film. All patients underwent cone-beam CT (CBCT) examinations before and 3, 6, and 12 months after the operation to determine the bone mineral density in the bone defect area. Results: No recurrence occurred in all patients. The comparison of HUT value in CBCT examination showed that the difference between the three groups before operation was not statistically significant (P>0.05); the difference was significant at different times within the group (P<0.05), and the HUT value gradually increased with the passage of time; The differences between the three groups at 3, 6, and 12 months were statistically significant (P<0.05), and the C group was significantly larger than the A and B groups (P<0.05), and the B group was significantly larger than the C group (P<0.05). Conclusion: The repairing membrane combined with β-TCP in the treatment of bone defects after jaw cyst has an ideal osteogenic effect and high clinical value.