Abstract:Objective To compare the value of color Doppler echocardiography (CDE) and computed tomography angiography (CTA) in the differential diagnosis of partial and total anomalous pulmonary venous drainage in children.Methods A total of 92 children with anomalous pulmonary venous drainage confirmed in surgery admitted to our hospital from March 2010 to April 2019 were selected. Both CDE and CTA were carried out before the operation, and the surgery was taken as the gold standard to confirm the presence of anomalous pulmonary venous drainage. The typical features and diagnostic results of the two methods were recorded. The values of the two methods in differential diagnosis of partial and total anomalous pulmonary venous drainage, and the accuracy rates of two methods in diagnosis of total anomalous pulmonary venous drainage subtypes and the distribution of pulmonary vein were compared.Results As observed in surgery, 72 cases were partial anomalous pulmonary venous drainage and 20 cases were total anomalous pulmonary venous drainage. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of CDE, CTA, and the combination of CDE and CTA in differential diagnosis of partial and total anomalous pulmonary venous drainage were comparable (P > 0.05). The sensitivity, specificity, accuracy, positive predictive value, negative predictive value of CDE and CTA were also similar in the diagnosis of supracardiac, cardiac, infracardiac and mixed types of total anomalous pulmonary venous drainage (P > 0.05).Conclusions The values of CDE in differential diagnosis of partial and total anomalous pulmonary venous drainage as well as the diagnosis of total anomalous pulmonary venous drainage subtypes in children are similar to those of CTA. However, CDE is safer, easier to carry out and more repeatable, and is therefore preferred.