心外膜脂肪组织密度对冠状动脉粥样硬化性心脏病的诊断价值

Diagnostic value of epicardial adipose tissue density in coronary atherosclerotic heart disease

摘要:

心外膜脂肪组织是围绕在心肌与冠状动脉周围的一种特殊内脏脂肪组织，可产生内源性促炎因子，通过旁分泌途径影响冠状动脉粥样硬化的发生、发展。CT测量的心外膜脂肪组织密度可能为早期识别冠状动脉粥样硬化和冠状动脉粥样硬化性心脏病危险分层提供影像学依据。该文主要就CT测量心外膜脂肪组织密度的方法及其在冠状动脉粥样硬化性心脏病中的应用进展作一综述。

Abstract:

Epicardial adipose tissue, as a special visceral adipose tissue surrounding myocardium and coronary artery, can produce endogenous proinflammatory factors to affect the occurrence and development of coronary atherosclerosis through paracrine pathway. CT-measured epicardial adipose tissue density may provide imaging basis for early identification of coronary atherosclerosis and risk stratification of coronary atherosclerotic heart disease. This review mainly summarizes the progress of epicardial adipose tissue density in coronary atherosclerotic heart disease and the measurement of CT-derived epicardial adipose tissue density is reviewed in this article.