同时性多原发结直肠癌研究进展

Research progress of synchronous colorectal cancer

摘要:

同时性多原发结直肠癌是一类特殊类型的大肠癌疾病，指同一患者同时或6个月以内于结直肠诊断2个或2个以上相互独立的肠癌病灶。近年来随着临床诊治水平的提高及人类平均寿命的延长，同时性多原发结直肠癌的发病率明显升高。该疾病与孤立性结直肠癌相比，具有其独特的临床病理特征，且临床漏诊率较高，因此提高对这一特殊类型大肠癌的认识具有重要的临床意义。目前关于同时性多原发结直肠癌的病因及发病机制尚不明确，该文针对同时性多原发结直肠癌的临床、病理特点及分子特征、诊治等进行文献综述，以提高临床医生对该疾病的认识，指导临床诊治。

Abstract:

Synchronous colorectal cancer (SCRC) is a special type of colorectal cancer. It refers to two or more independent colon cancer lesions were diagnosised at the same time or within 6 months in a person.In recent years, with the improvement of medical diagnosis and treatment technology and the extension of human life expectancy, the incidence of synchronous colorectal cancer has increased significantly.Compared with solitary colorectal cancer, this disease has its unique clinicopathological characteristics and a high rate of clinical misdiagnosis. Therefore, improving the understanding of this special type of colorectal cancer has important significance.At present, the etiology and pathogenesis of synchronous colorectal cancerr are not clear.This article reviews the clinical, pathological,molecular characteristics and treatment of synchronous colorectal cancer in order to improve the knowledge of clinicians and guide clinical diagnosis and treatment.