蜂针治疗过敏性鼻炎患者的疗效分析及免疫学指标变化

Therapeutic efficacy of bee acupuncture in patients with allergic rhinitis and alterations in immunological indicators

摘要:

目的 分析过敏性鼻炎患者应用蜂针治疗的效果，并分析其对免疫学指标的影响。方法 回顾性分析2017年6月—2019年6月在广州医科大学附属第五医院治疗的80例过敏鼻炎患者的临床资料，按疗法分为对照组和观察组，每组40例。对照组行常规西药治疗，观察组行蜂针治疗。对比两组治疗前后的症状、免疫学指标、生活质量改善情况。结果 观察组治疗前后鼻炎伴随症状总评价表评分、鼻症状评分的差值均大于对照组（P <0.05）。观察组治疗前后血清免疫球蛋白E、γ干扰素、白细胞介素4、白细胞介素6的差值均大于对照组（P <0.05）。观察组治疗前后鼻结膜炎生存质量调查问卷评分的差值均大于对照组（P <0.05）。结论 蜂针可有效缓解过敏性鼻炎症状，增强免疫力，提高生活质量，可在临床推广应用。

Abstract:

Objective To analyze the therapeutic efficacy of bee acupuncture in patients with allergic rhinitis, and to explore its effects on the immunological indicators.Methods The clinical data of 80 patients with allergic rhinitis who were treated in our hospital from June 2017 to June 2019 were analyzed retrospectively. The patients were divided into two groups, namely control group (n = 40) treated with conventional Western medicine, and observation group (n = 40) treated with bee acupuncture. The improvements of symptoms, immunological indicators and quality of life before and after the treatment were compared between the two groups.Results The differences of all the item scores of the Total Non-Nasal Symptom Score (TNNSS) and Total Nasal Symptom Score (TNSS) before and after the treatment were greater in the observation group than those in the control group (P < 0.05). The differences of serum levels of immunoglobulin E, interferon-γ, interleukin-4 and interleukin-6 before and after the treatment in the observation group were higher than those in the control group (P < 0.05). In addition, the differences of the total score and item scores of Rhinoconjunctivitis Quality of Life Questionnaire before and after the treatment were also higher in the observation group relative to those in the control group (P < 0.05).Conclusions Bee acupuncture is effective for relieving the symptoms of allergic rhinitis and ameliorating the levels of immunological indicators. Apart from improving the curative effect, bee acupuncture also reduces the impact of the disease on daily life. Thus, bee acupuncture is of great value for further researches.