急性呼吸窘迫综合征发病机制及相关生物标志物的研究进展

Pathophysiological mechanism of acute respiratory distress syndrome and research progress on diagnostic biomarkers of ARDS

摘要:

急性呼吸窘迫综合征（ARDS）是一类常见的临床重症，异质性强，病死率高，目前诊断主要依据柏林定义，敏感性和特异性均较差。该研究从其病理生理学机制出发，综述其诊断的生物标志物，以帮助临床提高其诊断的敏感性和特异性。

Abstract:

Acute respiratory distress syndrome (ARDS) is a common clinical severe disease with strong heterogeneity and high mortality. At present, the diagnosis is mainly based on the Berlin definition, with poor sensitivity and specificity. We hope to find appropriate biomarkers to improve its diagnostic sensitivity and specificity.