润房镜联合普拉洛芬滴眼液对白内障术后中重度干眼症的疗效分析

Efficacy of moisturizing mirror combined with Pranoprofen eye drops on moderate to severe dry eye after cataract surgery

摘要:

目的 探讨润房镜联合普拉洛芬滴眼液对白内障术后中重度干眼症的疗效。方法 选取2020年3月—2021年8月崇州市人民医院收治的108例白内障术后中重度干眼症患者，采用随机数字表法分为对照组（采用普拉洛芬滴眼液治疗）和联合组（采用润房镜+普拉洛芬滴眼液治疗），每组54例。比较两组患者的泪膜破裂时间（BUT）、泪液分泌试验（SIT）、眼表疾病指数（OSDI）、角膜荧光素染色评分（FL）、临床疗效、视觉质量及不良反应。结果 联合组治疗前后BUT、SIT的差值高于对照组（P <0.05）。联合组治疗前后OSDI、FL评分的差值高于对照组（P <0.05）。联合组总有效率高于对照组（P <0.05）。联合组与对照组治疗期间不良反应总发生率比较，差异无统计学意义（P >0.05）。结论 润房镜联合普拉洛芬滴眼液治疗白内障术后中重度干眼症可改善临床症状，提高临床疗效和视觉质量，且安全可靠。

Abstract:

Objective To investigate the curative effect of Moisturizing mirror combined with Pranoprofen eye drops on moderate to severe dry eye after cataract surgery.Methods From March 2020 to August 2021, 108 patients with moderate to severe dry eye after cataract surgery were selected and divided into the control group (treated with Pranoprofen eye drops) and the combined group (treated with praprofen eye drops) by random number table method, 54 cases in each group. The tear break-up time (BUT), tear secretion test (SIT), ocular surface disease index (OSDI), corneal fluorescein staining score (FL), clinical efficacy, visual quality, and adverse reactions were compared between the two groups.Results The difference of BUT and SIT in the combined group before and after treatment was higher than that in the control group (P < 0.05). The difference of OSDI and FL scores in the combination group before and after treatment was higher than that in the control group (P < 0.05). The total effective rate of the combined group was higher than that of the control group (P < 0.05). There was no significant difference in the total incidence of adverse reactions between the combination group and the control group during treatment (P > 0.05).Conclusion Moisturizing mirror combined with pranoprofen eye drops can improve clinical symptoms, improve clinical efficacy, and visual quality in the treatment of moderate to severe dry eye after cataract surgery, and is safe and reliable.