ATF4作用机制与相关疾病的研究进展

Research progress of ATF4 gene

摘要:

激活转录因子4（ATF4）是激活转录因子中的一种基因，其功能多样，作用范围广，参与作用多种生物学过程。该文介绍ATF4在生理机制、疾病发展过程及治疗靶点中相关功能的研究进展，为其在心脑血管疾病、肿瘤、血液系统疾病中的应用提供理论支持及新思路。

Abstract:

Activating transcription factor 4 (ATF4) is one of the genes that activate transcription factors. It has diverse functions and a wide range of functions. Multiple biological processes have to be involved with ATF4. This paper presents the progress of research on the functions of ATF4 in physiological mechanisms, disease development processes and therapeutic targets. It is expected to provide theoretical support and new ideas for the application of this gene in cardiovascular and cerebrovascular diseases, tumors, and hematologic diseases.