疏气定痛方化裁联合经皮穴位电刺激治疗老年慢性盆腔炎患者的疗效分析

Efficacy of modified Shuqi Dingtong Formula combined with transcutaneous electrical acupoint stimulation in treating elderly patients with chronic pelvic inflammatory disease

摘要:

目的 探讨疏气定痛方化裁联合经皮穴位电刺激（TEAS）在老年慢性盆腔炎患者中的应用效果。方法 选取2018年2月—2021年3月贵阳市妇幼保健院收治的老年慢性盆腔炎患者，按照随机数字表法分为对照组（常规治疗）和观察组（常规治疗联合疏气定痛方化裁），每组60例。对比两组患者临床疗效，治疗前后主要症状中医证候积分、免疫学指标及血流动力学指标；记录两组治疗期间不良反应发生情况；治疗后随访6个月，对比两组患者复发情况。结果 观察组总有效率高于对照组（P <0.05）；观察组治疗前后带下异常、腰骶胀痛、下腹胀痛、神疲乏力症状积分的差值均高于对照组（P <0.05）；观察组治疗前后CD3⁺、CD4⁺、CD4⁺/CD8⁺、CD8⁺的变化均大于对照组（P <0.05）；观察组治疗前后红细胞电泳时间、血沉率及血浆黏度的差值均高于对照组（P <0.05）；两组患者治疗过程中均未出现不良反应，随访6个月后，观察组复发率低于对照组（P <0.05）。结论 对老年慢性盆腔炎患者予以疏气定痛方化裁联合TEAS疗效显著，可有效降低中医证候积分，提高机体免疫力，还可改善血液流变学，且复发率低。

Abstract:

Objective To investigate the efficacy of modified Shuqi Dingtong Formula combined with transcutaneous electrical acupoint stimulation (TEAS) in the treatment of elderly patients with chronic pelvic inflammatory disease.Methods The elderly patients with chronic pelvic inflammatory disease admitted to our hospital from February 2018 to March 2021 were selected and randomly divided into the control group (conventional treatment) and the observation group (conventional treatment and modified Shuqi Dingtong Formula combined with TEAS), with 60 cases in each group. The clinical efficacy of the two groups was compared. The TCM syndrome scores, immunological indicators and hemodynamic parameters before and after treatment were analyzed. The adverse reactions of the two groups during treatment were recorded. After treatment, the patients in the two groups were followed up for 6 months to observe the recurrence of the disease.Results The overall effective rate of the observation group was significantly higher than that of the control group (P < 0.05). The differences of the scores of abnormal leukorrhea, lumbosacral pain, lower abdominal pain and distension and fatigue before and after treatment in the observation group were higher than those in the control group (P < 0.05). The differences of the frequency of CD3⁺, CD4⁺ and CD8⁺ cells as well as the ratio of CD4⁺/CD8⁺ cells before and after treatment in the observation group were higher than those in the control group (P < 0.05). The differences of erythrocyte electrophoresis time, erythrocyte sedimentation rate and plasma viscosity before and after treatment in the observation group were higher than those in the control group (P < 0.05). There was no adverse reaction in the two groups during treatment. After 6 months of follow-up, the recurrence rate in the observation group was lower than that in the control group (P < 0.05).Conclusions Modified Shuqi Dingtong Formula combined with TEAS can effectively reduce TCM syndrome scores, improve the immune function and hemodynamic parameters, and reduce the recurrence rate in elderly patients with chronic pelvic inflammatory disease.