Abstract:Objective To investigate the effect of combining hollow screw internal fixation with locking plate on the healing outcomes and ankle joint function in patients with ankle fractures.Methods A total of 84 patients with ankle fractures, treated between January 2021 and January 2023 at the 901st Hospital of the Joint Logistics Support Force, were selected for the study. Patients were randomly divided into a control group and an observation group, each consisting of 42 patients. The control group underwent open reduction and internal fixation using standard plates and Kirschner wires, while the observation group received locking plates combined with hollow screw fixation. Postoperative parameters recorded included time to ambulation, duration of hospitalization, and fracture healing time. Serum levels of interleukin-6 (IL-6), IL-8, and C-reactive protein (CRP) were measured preoperatively and 3 months postoperatively. Ankle joint range of motion (dorsiflexion, plantarflexion, inversion, and eversion) and radiographic indicators (tibiotalar angle [TAS], talar tilt [TT], tibial plafond angle [TC], and lateral tibial surface angle [TLS]) were compared preoperatively and 2 years postoperatively. Ankle function was assessed using the American Orthopaedic Foot & Ankle Society (AOFAS) score at 2 years post-surgery. Complications within 3 months postoperatively, such as wound infection, hematoma, and malunion, were also recorded.Results The observation group showed significantly shorter times to ambulation, hospital stays, and fracture healing compared to the control group (P <0.05). The differences in IL-6, IL-8, and CRP levels at 3 months postoperatively were lower in the observation group (P <0.05). At 2 years postoperatively, the observation group had superior ankle range of motion and higher TAS, TC, TLS, and AOFAS scores, with lower TT differences and a lower overall complication rate compared to the control group (P <0.05).Conclusion Combining hollow screw internal fixation with locking plate fixation in the treatment of ankle fractures can significantly shorten healing time and improve postoperative ankle function.