Abstract:Objective To explore the value of ultrasound elastography combined with two-dimensional ultrasound in the diagnosis of deep vein thrombosis (DVT) of lower limbs.Method A total of 100 suspected DVT patients admitted to the Ultrasound Department of Hefei First People's Hospital from January 2020 to December 2022 were selected as the research objects, and their related clinical data were reviewed. Their general data, two-dimensional ultrasound examination results and lower limb deep vein angiography results, ultrasonic elastography scores and strain values were compared, and the value of ultrasonic elastography combined with two-dimensional ultrasound in the diagnosis of lower limb deep vein thrombosis was analyzed.Result Among the 100 patients with suspected DVT, 34 were diagnosed with DVT and 66 were diagnosed with non-DVT after deep venography of the lower extremities. Thirty-four patients with DVT were enrolled in the DVT group and 66 patients with non-DVT were enrolled in the non-DVT group. There was no significant difference in gender composition, body mass index, prevalence of hypertension, prevalence of diabetes mellitus and prevalence of hyperlipidemia between DVT patients and non-DVT patients (P >0.05). The sensitivity and specificity of two-dimensional ultrasound for the diagnosis of DVT were 73.53% (25/34) and 92.42% (61/66). The sensitivity and specificity of ultrasound elastography in the diagnosis of DVT were 82.35% (28/34) and 84.85% (56/66). The sensitivity, ultrasound elastography, and ultrasound elastography combined with two-dimensional ultrasound diagnosis were 73.53% (95% CI: 0.697, 0.970), 82.35% (95% CI: 0.589, 0.862) and 88.24% (95% CI: 0.673, 0.909), respectively, and the specificity was 92.42% (95% CI: 0.806, 0.937), 84.85% (95% CI: 0.823, 0.958), and 89.39% (95% CI: 0.868, 0.977).Conclusion Ultrasound elastography combined with two-dimensional ultrasound is of high value in the diagnosis of lower limb deep vein thrombosis and can be widely used in clinical practice.