基于免疫细胞再生障碍性贫血发病机制的研究进展

Research progress on the pathogenesis of aplastic anemia based on immune cells

摘要:

再生障碍性贫血（AA）是由多因素引起的骨髓造血功能降低或衰竭的血液系统疾病。该文对近年来AA发病机制有关T淋巴细胞、B淋巴细胞、自然杀伤细胞、树突状细胞、巨噬细胞等免疫细胞的报道进行综述，为今后深入研究AA发病机制与新治疗靶点提供证据和思路。

Abstract:

Aplastic anemia (AA) is a hematological disorder characterized by reduction or failure of bone marrow hematopoiesis caused by multiple factors. This article reviews recent reports on the pathogenesis of AA related to immune cells, including T lymphocytes, B lymphocytes, NK cells, dendritic cells, and macrophages. It provides evidence and perspectives for further research on the pathogenesis and new therapeutic targets of AA.