Abstract:Objective To compare the effect of self-etching and self-bonding flow resin and new bulk resin in repairing caries on the adjacent surface of deciduous molar teeth.Methods The data of 93 children with caries on the adjacent surface of primary molars admitted to Qingdao Central Hospital of Rehabilitation University from January 2020 ~ August 2023 were reviewed, and the patients were divided into the study group (47 cases) and the control group (46 cases) according to different filling materials, among which the control group was treated with a new bulk resin and the research group was treated with self-etching and self-bonding flow resin. The restoration effect, occlusal function, periodontal indexes, periodontal inflammatory factors and complications were compared between the two groups.Results There was no significant difference in the repair effect between the control group and the study group (P >0.05). There was no significant difference between the control group and the study group in terms of maximum bite force and chewing efficiency before and after treatment (P >0.05). There was no significant difference between the control group and the study group before and after treatment of periodontal indexes SBI, GI and PLI (P >0.05). The difference of periodontal inflammation in the study group was higher than that in the control group (P <0.05) due to TNF-α, IL-6 and IL-8 levels before and after treatment. There was no significant difference in the total complication rate between the control group and the study group (P >0.05).Conclusion Both the self-etching and self-bonding flow resin and the new bulk resin can achieve satisfactory results in the repair of dental caries on the adjacent surface of deciduous molar teeth, and obtain good occluding function and periodontal indexes, which is safe and reliable. However, the self-etching and self-bonding flow resin has more advantages in inhibiting periodontal inflammation.