原发性甲状旁腺功能亢进症的临床定位诊断进展

Advances in clinical localization diagnosis of primary hyperparathyroidism

摘要:

原发性甲状旁腺功能亢进症（PHPT）以高血钙和甲状旁腺激素水平超出正常范围为特征。时至今日，PHPT依然是导致门诊高钙血症的重要原因之一。最新的临床诊断进展大大提高了识别该内分泌疾病的准确性与效率。通过整合多种成像技术和生化指标，诊断流程得到了加强。借助成像技术对甲状旁腺肿瘤进行术前定位的能力显著提升。术前的精准定位对于实现甲状旁腺病变的完全切除起到了重要作用。该综述深入探讨PHPT在临床诊断中的最新进展。

Abstract:

Primary hyperparathyroidism (PHPT), characterized by hypercalcemia and elevated parathyroid hormone (PTH) levels, remains a significant cause of outpatient hypercalcemia. Recent advances in clinical diagnostics have substantially enhanced the accuracy and efficiency of identifying this endocrine disorder. The diagnostic pathway has been optimized through synergistic integration of multiple imaging modalities and biochemical indicators. Preoperative tumor localization capability has been revolutionized by advanced imaging techniques, enabling precise surgical targeting. This review critically appraises contemporary progress in PHPT localization diagnostics.