重症肺炎支原体肺炎患儿免疫功能变化的临床研究进展

Clinical research progress on immune function changes in children with severe Mycoplasma pneumoniae pneumonia

摘要:

近年来，肺炎支原体肺炎的发病率逐渐增加，儿童重症肺炎支原体肺炎的比例也呈上升趋势。重症肺炎支原体肺炎不仅引起严重的呼吸道症状，还常伴有肺外并发症，极大地危害儿童健康。免疫紊乱与重症肺炎支原体肺炎的发生、发展和预后密切相关，监测患儿的免疫指标有助于评估病情进展并制订合理的治疗方案。该文综述重症肺炎支原体肺炎的免疫功能变化及其临床意义，旨在为其早期识别和个体化治疗提供参考。

Abstract:

In recent years, the incidence of Mycoplasma pneumoniae pneumonia (MPP) has gradually increased, and the proportion of severe Mycoplasma pneumoniae pneumonia (SMPP) in children has also shown an upward trend. SMPP not only causes severe respiratory symptoms but is frequently associated with extrapulmonary complications, posing significant threats to children's health. Immune dysregulation is closely linked to the pathogenesis, progression, and prognosis of SMPP. Monitoring immune parameters in affected children aids in evaluating disease progression and formulating individualized treatment plans. This article reviews alterations in immune function and their clinical implications in SMPP, aiming to provide evidence for early identification and targeted therapeutic strategies.