结直肠癌患者益处发现联合促进方案的实证研究

An empirical study on the integrated benefit-finding promotion program for colorectal cancer patients

摘要:

目的 评估课题组前期构建的《结直肠癌患者益处发现中西医联合促进方案》的临床效果，探究其对患者益处发现水平及心理健康指标的影响。方法 采用整群随机对照研究设计，于2023年7月—2024年6月便利抽取湖南师范大学附属长沙医院收治的结直肠癌（CRC）患者64例。采用随机区组实验设计法分为对照组（32例，完成30例）和干预组（32例，完成28例）。对照组接受常规治疗，干预组在常规治疗基础上实施中西医联合促进方案。采用益处发现量表和欧洲癌症研究与治疗组织生活质量核心量表评估干预效果。结果 经过8周干预，干预组益处发现总分高于对照组（P <0.05）。生活质量评估显示，干预组在躯体功能、角色功能、情绪功能、社会功能、认知功能及整体健康状况等维度得分均高于对照组（P <0.05）。结论 中西医联合促进方案能有效提升CRC患者的益处发现水平，并在改善躯体、情绪和社会功能等生活质量核心指标方面具有显著优势，对改善患者生活质量具有积极影响。

Abstract:

Objective To evaluate the clinical efficacy of the integrated Chinese-Western medicine benefit-finding promotion program for colorectal cancer (CRC) patients and its impact on benefit-finding levels and psychological health indicators.Methods Using a cluster randomized controlled design, 64 CRC patients from Changsha Hospital Affiliated to Hunan Normal University (July 2023-June 2024) were assigned to control group (n = 32, 30 completed) or intervention group (n = 32, 28 completed). The control group received conventional treatment; the intervention group received additional integrated Chinese-Western medicine promotion. The Benefit Finding Scale and EORTC QLQ-C30 assessed outcomes.Results After 8-week intervention, the intervention group demonstrated significantly higher total benefit-finding scores versus control group (P < 0.05). Quality of life assessment showed superior performance in physical, role, emotional, social, and cognitive functioning domains, along with global health status in the intervention group (P < 0.05).Conclusion The integrated Chinese-Western medicine program effectively enhances benefit-finding levels and improves core quality-of-life indicators in CRC patients.