Abstract:Objective To investigate the effectiveness of Thunder-Fire Moxibustion combined with active pain management in patients experiencing postoperative pain after ankle fracture surgery.Methods A total of 82 patients with ankle fractures admitted to our hospital from January 2022 to January 2024 were selected and divided into a control group and an observation group (each n = 41) by the random number table method. Both groups received conventional rehabilitation training starting one day after surgery. The control group received active pain management in addition to conventional rehabilitation, while the observation group underwent Thunder-Fire Moxibustion combined with the regimen in the control group. Pain scores and ankle swelling were recorded before and 1 week and 4 weeks after treatment. The levels of inflammatory factors, ankle range of motion (ROM), and ankle function assessed by the American Orthopaedic Foot & Ankle Society (AOFAS) scores were compared between the two groups before treatment and 4 weeks after treatment.Results A comparison was made between the observation group and the control group regarding Visual Analog Scale (VAS) scores and joint swelling severity before treatment, one week after treatment, and four weeks after treatment, which demonstrated that they were different across the time points (F = 362.094 and 1 512.463, both P < 0.05) and between the groups (F = 11.054 and 34.932, both P < 0.05), with lower VAS scores and joint swelling severity in the observation group. The change trends of VAS scores and joint swelling severity were also different between the two groups (F = 3.302 and 12.971, both P < 0.05). There was no difference in interleukin-6 (IL-6) and C-reactive protein (CRP) levels before treatment between the two groups (P > 0.05). After treatment, the observation group exhibited significantly lower levels of IL-6 and CRP compared with the control group (P < 0.05). Both groups showed a significant decrease in IL-6 and CRP levels after treatment compared with baseline (P < 0.05), with the magnitude of change in the observation group being greater than that in the control group (P < 0.05). Before treatment, there were no significant differences between the two groups in dorsiflexion, plantarflexion, inversion, or eversion angles (P > 0.05). After treatment, the observation group showed significantly greater improvements in all these ankle range-of-motion parameters compared with the control group (P < 0.05). Both groups experienced significant increases in dorsiflexion, plantarflexion, inversion, and eversion angles after treatment compared with baseline (P < 0.05), with the changes in the observation group exceeding those in the control group (P < 0.05). Similarly, pre-treatment scores for pain, function, and alignment did not differ significantly between the two groups (P > 0.05). After treatment, the observation group had significantly higher scores in pain, function, and alignment compared with the control group (P < 0.05). Both groups showed significant improvements after treatment relative to baseline (P < 0.05), with the magnitude of improvement in the observation group being greater than that in the control group (P < 0.05).Conclusions Thunder-Fire Moxibustion combined with active pain management effectively reduces postoperative pain and improves joint function in patients with ankle fractures.