Abstract:Objective To investigate the clinical effect of multilevel hemilaminectomy under fully-visualized percutaneous posterior spinal endoscopy with spinal canal decompression and enlargement in patients with cervical spinal stenosis (CS).Methods Sixty cases of CS patients admitted to our hospital from August 2023 to December 2024 were selected and divided into 30 cases in the control group and 30 cases in the treatment group using a random number table. The control group underwent posterior open-door laminoplasty, and the treatment group was treated with multilevel hemilaminectomy under fully-visualized percutaneous posterior spinal endoscopy with spinal canal decompression and enlargement. The perioperative indicators, radiographic outcomes, Japanese Orthopaedic Association (JOA) scores, Neck Disability Index (NDI) scores, visual analog scale (VAS) scores, and incidence of complications were compared between the two groups.Results The control group had longer operative duration and length of hospital stay than the treatment group (P < 0.05), and intraoperative blood loss was greater in the control group than in the treatment group (P < 0.05). The JOA improvement rate in the treatment group was higher than that in the control group (P < 0.05). Postoperative NDI and VAS scores in the treatment group were lower than those in the control group (P < 0.05). Postoperative NDI and VAS scores in both groups were lower than preoperative scores (P < 0.05). The differences in NDI and VAS scores before and after surgery in the treatment group were greater than those in the control group (P < 0.05). The postoperative C1~C2 Cobb angle in the treatment group was greater than that in the control group (P < 0.05). Postoperative C1~C2 Cobb angles in both groups were larger than preoperative values (P < 0.05), while C2~C7 Cobb angles were smaller than preoperative values (P < 0.05). The differences in C1~C2 Cobb angles and C2~C7 Cobb angles before and after surgery in the treatment group were greater than those in the control group (P < 0.05). There was no statistically significant difference in the overall incidence of complications between the control group and the treatment group (P > 0.05).Conclusion Multilevel hemilaminectomy under fully-visualized percutaneous posterior spinal endoscopy with spinal canal decompression and enlargement provides definite clinical benefits for patients with CS, including shorter operative duration and length of hospital stay, reduced intraoperative blood loss, effective symptom relief, improved cervical function, and enhanced postoperative recovery.