Abstract:Objective To analyze the application effect of "Hourglass Sign" iliofascial-sacral plexus block combined with general anesthesia in elderly patients undergoing total hip arthroplasty (THA).Methods A total of 83 elderly patients who underwent THA in The 904th Hospital of Joint Logistics Support Force of Chinese People's Liberation Army from January 2022 to January 2024 were selected and divided into two groups according to the envelope method. The control group (n = 40) received general anesthesia, and the observation group (n = 43) received "Hourglass Sign" iliofascial-sacral plexus block combined with general anesthesia. The anesthetic effects of the two groups were compared.Results Compared with the control group, the observation group had less intraoperative blood loss, faster postoperative pain relief, more significant improvement in stress indicators, fewer patient-controlled analgesia pump presses and lower rescue analgesic dosage (P < 0.05). Hemodynamics fluctuated at different time points postoperatively compared with preoperatively in both groups, but the overall changes in the observation group were more stable (P < 0.05). Postoperative Visual Analog Scale (VAS) scores decreased significantly in both groups compared with preoperative scores (P < 0.05), with lower scores in the observation group (P < 0.05). The observation group had a greater decrease in postoperative stress indicators (P < 0.05). There was no statistically significant difference in the incidence of complications between the observation group and the control group (P > 0.05).Conclusion The combination of "Hourglass Sign" iliofascial-sacral plexus block and general anesthesia has a significant effect. It can effectively maintain hemodynamic stability, reduce stress responses, alleviate the degree of pain in patients, with a low incidence of adverse reactions.