肺动脉高压危险因素及早期风险预测模型的研究进展

Research progress on risk factors and early risk prediction models of pulmonary hypertension

摘要:

肺动脉高压（PH）是一种以肺血管重塑、进行性肺动脉压力升高及右心室功能衰竭为特征的严重心血管疾病。随着对PH病理生理机制认识的深入与诊断技术的不断进步，实现PH高危人群的早期识别并建立精准的预测模型，已成为当前研究的重要方向。该文综述了PH危险因素的研究进展及PH早期风险预测模型，旨在为临床早期发现PH高风险患者并制订有效防治措施提供科学依据，同时为构建更精准的PH预测模型提供新的思路与参考。

Abstract:

Pulmonary hypertension (PH) is a severe cardiovascular disease characterized by pulmonary vascular remodeling, progressive elevation of pulmonary arterial pressure, and right ventricular failure. With advances in understanding PH pathophysiology and diagnostic technologies, early identification of high-risk populations and construction of precise predictive models have emerged as pivotal research priorities. This review summarizes current research progress on PH risk factors and early risk prediction models, aiming to provide scientific evidence for early detection of high-risk patients and development of effective preventive and therapeutic strategies, and to offer novel insights for developing more accurate PH predictive models.