神经重症患者非惊厥性癫痫持续状态的早期预防及分步治疗研究进展

Advances in early prevention and stepwise treatment of non-convulsive status epilepticus in neurocritically ill patients

摘要:

神经重症监护病房的患者通常具有非惊厥性癫痫持续状态发作的高风险，但其症状通常不典型，常导致诊断和治疗延迟，使发生非惊厥性癫痫持续状态患者的残疾率、病死率增加。目前连续脑电图的使用推动了非惊厥性癫痫持续状态的早期识别，并提出了治疗的分步方法。笔者总结了神经重症监护病房中非惊厥性癫痫持续状态早期预防及当前的治疗进展，并概述了进一步研究的领域。

Abstract:

Patients in the neurological intensive care unit are often at high risks for non-convulsive status epilepticus, but their symptoms are usually atypical. Thus, it may lead to delays in diagnosis and treatment and increased disability rate and mortality in patients who develop non-convulsive status epilepticus. The current application of continuous EEG has promoted the early identification of non-convulsive status epilepticus and suggested a stepwise approach to dealing with the condition. In this review, we summarize the advances in the early prevention and treatment of non-convulsive status epilepticus among the neurocritically ill patients, and outline areas for further research.